Zebra ZD421

The Zebra ZD421 is one of the most popular 4-inch desktop label printers on the market — the direct successor to the legendary GK420 series. It combines a compact footprint with field-installable connectivity options (USB, Ethernet, Wi-Fi, Bluetooth), fast print speeds up to 152 mm/s and Zebra Print DNA software tools, making it the go-to choice for shipping labels, retail price tags, healthcare wristbands and light industrial labelling.

Which Zebra ZD421 model should you choose?

Model	Print technology	Best for	Ribbon
ZD421d	Direct thermal	Shipping labels (Omniva, DPD, Itella/Smartpost), receipts, short-life labels	No ribbon needed
ZD421t	Thermal transfer + direct thermal	Product labels, barcode labels, asset tags that must last years	Standard 74 m / 300 m ribbons
ZD421c	Thermal transfer (cartridge)	Offices and teams that want tool-free, mess-free ribbon changes in seconds	Easy-load ribbon cartridge
ZD421-HC	Direct thermal / thermal transfer	Healthcare: disinfectant-ready UV-resistant plastics, medical-grade power supply	Model dependent

Resolution: each model is available in 203 dpi (standard shipping and product labels) or 300 dpi (small labels, fine text, 2D barcodes, healthcare wristbands). Connectivity: all models include USB and USB Host; versions with Ethernet, Wi-Fi 802.11ac and Bluetooth 4.1 are listed below.

All Zebra ZD421 printers below ship with EU power supply and USB cable, are CE certified and covered by manufacturer warranty. Compatible thermal labels and thermal transfer ribbons are available from stock.

Need faster printing, UHF RFID encoding or a colour LCD? Step up to the Zebra ZD621 series →